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Enzyme Roundup

We analyzed 17 products to help you choose the healthiest & safest options.

Finding the perfect Enzyme shouldn't feel like a guessing game. At CakeID, we take food transparency seriously. We have analyzed over 17 products in this category, breaking down every ingredient list to uncover hidden additives, excessive sugar levels, and potential allergens.

Whether you are searching for strictly Vegan options, Gluten-Free snacks, or simply want to avoid high-processed foods, our algorithm ranks products based on a comprehensive Health Score. Below is our definitive ranking of the safest and healthiest Enzyme you can buy in 2026, sorted by their ingredient purity.

Editor's Quick Picks

Detailed Reviews

Calories
500
Sugar
100g
Garden of Life

Dr. Formulated Enzymes Organic Digest + Tropical Fruit

Ingredients: Organic Dextrose, Organic Gum Arabic, Organic Sunflower Lecithin, Organic Pineapple Flavor, Organic Banana Flavor

The Good

  • ● Clean Ingredients

The Bad

  • ● High Sugar Content
View Full Analysis
Calories
357
Protein
13g
pasta usa

Mataron & cheese

Ingredients: enriched wheat flour [wheat, niacin, ferrous sulfate (iron), thiamine mononitrate, riboflavin, folic acid], salt, contains 2% or less of: silicon dioxide to reduce caking, sodium phosphate, citric acid, soybean oil to reduce dusting, color added (yellow 5, yellow 6, yellow 6 lake, yellow 5 lake), maltodextrin, cheddar cheese* (pasteurized milk, cheese culture, salt, enzymes), cream*, sodium caseinate. *dehydrated contains wheat & milk. may contain egg.

The Good

  • ● Low Sugar

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Seeking Health

Digestive Enzymes

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Life Extension

Enhanced Super Digestive Enzymes And Probiotics Non-gmo

Ingredients: Protease SP (A. oryzae, B. subtilis), Bromelain (A. comosus), Lactase (A. oryzae), Cellulase (A. niger), Lipase (A. rugosa), Alpha-galactosidase (A. niger), Amylase (A. oryzae), Protease (A. niger), Xylanase (A. niger), Xylose Isomerase (A. niger), Bacillus coagulans MTCC5856, microcrystalline cellulose, hypromellose (capsule), maltodextrin, medium chain triglycerides, silica

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Thorne

Advanced Digestive Enzymes

Ingredients: Betaine Hydrochloride, L-Glutamic Acid Hydrochloride, Pancreatin (Porcine), Ox Bile concentrate, Pepsin (Porcine), Hypromellose (derived from cellulose) capsule, Calcium Laurate, Leucine

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Physician’s Choice

Digestive Enzymes

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
375
Sugar
0g
Sprouts

Daily fiber blend With enzymes and probiotics

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Nutricost

Digestive enzymes

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Physician's Choice

Digestive Enzymes With Prebiotics + Probiotics

Ingredients: Organic Inulin (from Jerusalem Artichoke), Organic Acacia Fiber, Inulin (from Chicory), Bacillus subtilis OPTIBIOME BS50β„’, Bacillus coagulans, Bacillus clausii, Organic Peppermint Leaf, Organic Ginger Root, Bromelain, Amylase, Protease 4.5, Glucoamylase, Protease 6.0, Papain, Lactase, Protease 3.0, Peptidase, Beta-Glucanase, Cellulase, Alpha-Galactosidase, Lipase, Xylanase, Hemicellulase, Invertase, Vegetable capsule (hypromellose), rice flour, rice hull

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Mary Ruth Organics

Mary Ruth's Ultra Digestive Food Enzymes

Ingredients: Thiamine, Vitamin B6, Vitamin B12, Calcium, Magnesium, Manganese, Amla, Phytase, Protease Blend, Amylase Blend, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, Beta-Glucanase, Hypromellose, Maltodextrin, and Calcium Phosphate.

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
BioOptimizers

Massenzymes

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Dr. Berg

Advanced Digestive Enzymes

Ingredients: Betaine hydrochloride, organic apple cider vinegar powder, pancreatin amylase, pancreatin protease, pancreatin lipase, pepsin, ginger root extract, peppermint leaf extract, anise seed powder, fennel seed extract, silicified microcrystalline cellulose, silicon dioxide, stearic acid, magnesium stearate

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Source Naturals

Essential Enzymes

Ingredients: hydroxypropyl methylcellulose (capsule), calcium sulfate, stearic acid, silica, magnesium stearate

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Natural Factors

Papaya Enzymes

Ingredients: Papain (Carica papaya) (fruit), Amylase (Aspergillus oryzae) (whole plant), Bromelain (Ananas comosus) (stem), Dextrose, fructose, natural orange colour (annatto, turmeric), Indian gooseberry, citric acid, natural papaya flavour, vegetable grade magnesium stearate (lubricant)

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
The Vitamin Shoppe

Multi-Enzyme

Ingredients: Calcium (as dicalcium phosphate), Betaine HCI, Pancreatin (4X USP)(porcine), providing: Protease, Amylase, Lipase, Pepsin (porcine)(1:3000), Ox Bile Powder (bovine), Papain (from papaya)(2000 FCCU units/mg), Amylase (Aspergillus oryzae)(30,000 SKB units/g), Protease (Aspergillus oryzae)(500,000 HUT units/g), Cellulase (Trichoderma reesei)(120,000 CU units/g), Lipase (Rhizopus oryzae)(5000 FIP units/g), Bromelain (from pineapple)(2400 GDU/g)

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
378
Protein
75g
Asitis Atom

Atom Whey Protein Enzyme Blend

Ingredients: Ingredients updating...

The Good

  • ● Excellent Health Score
  • ● Sugar Free
  • ● Clean Ingredients

The Bad

  • ● Ultra Processed
View Full Analysis
Calories
0
Sugar
0g
Physician’s Choice

Digestive Enzymes With Prebiotics + Probiotics

Ingredients: Organic inulin (from Jerusalem artichoke), organic acacia fiber, inulin (from chicory), Bacillus subtilis, Bacillus coagulans, Bacillus clausii, organic peppermint leaf, organic ginger root, bromelain, amylase, protease 4.5, glucoamylase, protease 6.0, papain, lactase, protease 3.0, peptidase, cellulase, beta-glucanase, alpha-galactosidase, lipase, xylanase, hemicellulase, invertase, vegetable capsule (hypromellose), rice flour, rice hull concentrate, gum arabic, sunflower oil

The Good

  • ● Excellent Health Score
  • ● Sugar Free

The Bad

  • ● Ultra Processed
View Full Analysis

Frequently Asked Questions

Are products in the Enzyme category always vegan?+
Not necessarily. We analyzed over 17 products in the Enzyme category on CakeID. While some are plant-based, many contain hidden animal ingredients like milk powder, whey, or gelatin. Always check the "Is Vegan" status on our product pages.
How does CakeID rank the best Enzyme?+
We rank Enzyme based on their nutritional value, ingredient cleanliness (fewer additives), and vegan compatibility. Products with lower sugar and simpler ingredients rank higher.
Can I find low-calorie Enzyme here?+
Yes! Our list highlights the nutritional details of each product. Look for the "Calories" badge on the product cards above to find low-calorie options.